Lenti-ONE VEGF165a

APPLICATIONS

  • Angiogenesis
  • Apoptosis, Oxidative Stress
  • CAR T-cells
  • CRISPR
  • Differentiation
  • Dominant Negative Mutants
  • Neurology, Ophthalmology
  • Optogenetics
  • Recombinases, Editors
  • Reporters and selection
  • RNA Interference

TRANSGENES

Lenti-ONE GFP

Lenti-ONE VEGF165a carries the VEGF165a cDNA. It encodes the vascular endothelial growth factor 165a (sequence from human genome, AF486837.1, 576 pb). This protein is a growth factor. It favors angiogenesis. It may also promote neuronal survival in experimental gene transfer assays.

Lenti-ONE VEGF165a

DESCRIPTION

VEGF165a SIGNALING PATHWAY IN ENDOTHELIAL CELLS

Lenti-ONE VEGF165a -

EXAMPLES OF APPLICATIONS

  • Use with flt1 promoter to target the expression in endothelial cells

  • Use in vitro or in vivo to induce angiogenesis

  • Use in vitro, in vivo to study cancer mechanisms

RESULTS

VEGF165a SIGNALING PATHWAY IN ENDOTHELIAL CELLS

 

Lenti-ONE VEGF165a -

Transduction of 293T cells in vitro with non-integrative Lenti-ONE VEGF121, VEGF165 or VEGF165b (100ng p24) induces transgene expression and VEGF secretion in cell culture medium (measured by ELISA).

Results provided by GEG Tech R&D

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