Lenti-ONE Bcl2

Description

Lenti-ONE Bcl-2 carries the cDNA of the B-cell CLL lymphoma 2 isoform alpha (sequence from human genome, NM_000633.2/CCDS 11981.1, 720 pb). This protein is an apoptosis regulating factor. By inhibiting the pro-apoptosis protein Bax, it promotes cellular survival.

bcl2-pathway

Examples of Applications

Use in vitro or in vivo to study apoptosis mechanisms
Use in vitro, in vivo to study cancer mechanisms

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