Transgenic animal models have become a key tool in fundamental research as well as in biomedical area. Indeed, animal models provide relevant insight and significantly improve our understanding of gene functions and disease mechanisms. Moreover, they are an invaluable tool to target discovery, validation, and production of therapeutic proteins.
Thanks to their efficiency and diversity of design, lentiviral vectors are a tool of choice to generate animal models in small species such as rodents but also in large species such as swine.
Diversity of design: