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Recent News about GEG Tech

  • Universal CAR T cell therapy helps beat a hard-to-treat pediatric cancer

    Universal CAR T cell therapy helps beat a hard-to-treat pediatric cancer

    February 23, 2021
  • Modified version of CAR T-cell therapy shows promise in targeting neuroblastoma

    Modified version of CAR T-cell therapy shows promise in targeting neuroblastoma

    February 8, 2021
  • Penn study opens the door to let CAR T cells reach the tumor microenvironment

    Penn study opens the door to let CAR T cells reach the tumor microenvironment

    January 28, 2021
  • GEG-tech signs Distribution Agreement with tebu-bio

    GEG-tech signs Distribution Agreement with tebu-bio

    March 2, 2020
  • Innovation in cancerology: meeting in Monaco

    Innovation in cancerology: meeting in Monaco

    January 28, 2020

The CAR T-Cells Revolution has begun

These past few months, cancer immunotherapy has sped-up thanks to CAR technology. One look at the recent news about this is enough to figure that out. As examples: Two major deals between pharmaceutical companies and biotechs specialized in CAR T-cells: Gilead bought Kite Pharma for $12 billion, and Celgene bought Juno Therapeutics…

  • June 26, 2018
  • Cancer immunotherapy

ANCHOR Technology

ANCHOR Technology / Partnership We are proud to annonce you that GEG Tech has validated the combination of the ANCHOR technology developed by NeoVirTech with our Lenti-ONE vectors. This  breakthrough technology allowed us to generate the first auto-fluorescent lentiviral vectors for live imaging and screening applications. For more details about the new possibilities offered by…

  • February 2, 2018
  • News

Live tracking of HIV-1 based lentiviral vectors

First-ever live tracking of HIV-1 based lentiviral vectors in human cells Technology breakthrough: visualization of lentivirus genomes in living cells using ANCHOR technology. We are proud to announce that we obtain great results through a collaborative project with NeoVirTech, a company developing auto fluorescent virus for imaging and screening applications….

  • January 11, 2018
  • Vectorology

Self-Inactivating KamiCas9 System

The Self-Inactivating KamiCas9 System for the Editing of CNS Disease Genes In this article, Merienne et al. designed a smart lentiviral vector system to improve the safety for genome editing of CNS disease gene. They characterized their CRISPR self-inactivating system (KamiCas9) for permanent disruption of huntingtin gene in the context…

  • October 4, 2017
  • Gene editing

Preclinical Evaluation of a Lentiviral Vector

Preclinical Evaluation of a Lentiviral Vector for Huntingtin Silencing Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder resulting from a polyglutamine expansion in the huntingtin (HTT) protein. There is currently no cure for this disease, but recent studies suggest that RNAi to downregulate the expression of both normal and…

  • September 4, 2017
  • Vectorology

Highly Efficient CRISPR/Cas9-Mediated Gene Editing

Integrase-Deficient Lentiviral Vector as an All-in-One Platform for Highly Efficient CRISPR/Cas9-Mediated Gene Editing The CRISPR/Cas9 systems have revolutionized the field of genome editing by providing unprecedented control over gene sequences and gene expression in many species, including humans. Lentiviral vectors (LVs) are an important means of delivering CRISPR/Cas9 components due…

  • August 2, 2017
  • Gene editing

Breast Cancer Research

Preclinical and Personalized Breast Cancer Research As scientists involved in life science research, we would like to let you know about the research project on breast cancer, led by the Brisken Lab in EPFL, Switzerland. The scientific team of GEG Tech is proud to be a part of it, designing…

  • May 11, 2017
  • News

Erythropoietin expression in dividing cells

Episomal lentiviral vectors confer erythropoietin expression in dividing cells Lentiviral vectors have evolved over the last decade as powerful and reliable gene transfer tools for dividing and non-dividing cells because they possess a large packaging capacity, weak immunogenesis, and a high flexible of design. However, in some cases, the integrating…

  • May 4, 2017
  • Vectorology

Evolution and Revolution

Genetic Engineering: Evolution and Revolution Over the last years, new genetic engineering technologies have emerged and undoubtedly show up game-changing. Genome engineering is since a long time explored and used because there is a lot at stake here in many fields. Indeed, the possibility to add, remove or change precisely…

  • April 3, 2017
  • Gene editing

Sendai virus for CRISPR/Cas9 delivery

Sendai virus, an RNA virus with no risk of genomic integration, delivers CRISPR/Cas9 for efficient gene editing A significant recent advance in genome engineering is the development of the CRISPR/Cas9 system for nuclease based genome editing. However, several cell types are not easily transfected and in vivo delivery of the…

  • October 10, 2016
  • Gene editing
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