New immunotherapy targets leukemia at its root

Acute myeloid leukemia (AML) is one of the most aggressive blood cancers, with poor response to chemotherapy or CAR-T cell therapy. This is notably due to a self-sustaining signaling loop that allows leukemia stem cells to grow and evade treatment. A study published in Nature Communications has just outlined a groundbreaking bispecific antibody that disrupts this mechanism. The […]