New approach reinvigorates exhausted T cells to improve tumor control
With continued exposure to tumours, T lymphocytes progressively lose their effectiveness due to the expression of co-inhibitory receptors that act as brakes. Exhausted T lymphocytes, which still retain some anti-cancer function, can deteriorate further until they reach a state of terminal exhaustion. Researchers found that a solute transporter called MCT11, which imports lactic acid, was […]