Researchers develop 3D organoid model to advance understanding of gastroesophageal junction cancer
Researchers have created a laboratory-developed, three-dimensional organoid model derived from human tissue and designed to understand the early stages of cancer in the gastroesophageal junction (GEJ), the point where the food pipe of the digestive system meets the stomach. Using CRISPR-Cas9, the researchers also eliminated two key tumor suppressor genes, TP53 and CDKN2A,c in the […]
