New DNA recombination toolbox surpasses CRISPR for genome engineering

Belgian researchers from the VIB-KU Leuven Center for Microbiology and the VIB-UGent Center for Plant Systems Biology have extended the toolbox that uses a viral recombinase (Cre) so that it can now specifically recognize, cut and paste multiple DNA sites. The team has identified a set of 16 sites that recombine efficiently with the same site, but not with any other site in that set, for different organisms. This new patented toolbox, complementary to CRISPR, and for some applications going beyond it, is now available to researchers and industrialists in the field of genome engineering. The results are reported today in two simultaneous articles in the prestigious journal Nature Communications.

New DNA recombination toolbox surpasses CRISPR for genome engineering - Blog

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