Post-translational covalent assembly of CAR and synNotch receptors for programmable antigen targeting | Nature Communications
Researchers have developed a universal receptor system that allows T cells to recognize any cell surface target, enabling highly customizable CAR T cell and other immunotherapies for treating cancer and other diseases. The new approach involves engineering T cells with receptors bearing a universal “SNAPtag” that fuses with antibodies targeting different proteins. By tweaking the […]