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Lenti-ONE GFP carries the transgene green fluorescent protein. Its expression can be assessed by fluorescent microscopy or by flow cytometry, thus giving valuable informations about the transduction efficiency of the vector.
Lenti-ONE Bcl-2 carries the cDNA of the B-cell CLL lymphoma 2 isoform alpha (sequence from human genome, NM_000633.2/CCDS 11981.1, 720 pb). This protein is an apoptosis regulating factor. By inhibiting the pro-apoptosis protein Bax, it promotes cellular survival.
